Administration
Rebif® (interferon beta-1a) offers many product features designed for convenience
- Rebif is shipped to you in prefilled, preassembled, ready-to-use syringes, so no premixing or assembly is required. Each Rebif injection requires 13 fewer steps than Betaseron® (interferon beta-1b) and Extavia® (interferon beta-1b) injections require.
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The Rebiject II® auto-injector—designed to make injections easier than a manual Rebif
injection. With the Rebiject II, the needle remains hidden both before and after injecting
Learn more about injection options and support to get you started with Rebif. -
3-times-weekly dosing schedule allows for injection-free weekends. Injections should be at least 48 hours apart.
- Copaxone® (glatiramer acetate injection) needs to be injected every single day, but Rebif needs to be injected only 3 times per week, which adds up to 209 fewer injections than Copaxone a year!
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Rebif is less than half the size of an Avonex® (interferon beta-1a) needle and is injected just
under the skin, not into the muscle.
*A 25-gauge, 1 inch needle for intramuscular injection may be substituted for the 23-gauge, 1¼ inch needle by the prescribing physician, if deemed appropriate. The higher the gauge, the thinner the needle. If a 1 inch needle is substituted, the needle for Rebif would be half the length of the needle for Avonex.
Although needles are shown to scale, they are not actual size.
Redness, pain or swelling at the injection site can occur with both injectable treatments.
- If refrigeration is not available, Rebif may be stored at or below room temperature (25°C/77°F) for up to 30 days and away from heat and light.
- If you're just starting on Rebif therapy, the Rebif Titration Pack includes premeasured, prefilled dosing. No mixing or measuring required!
- Rebif comes in two effective doses—22 mcg and 44 mcg. You and your doctor can decide which dose is right for you.
