Administration
Now available
Rebif® Rebidose® (interferon beta-1a)
New Rebif Rebidose is the latest way to take Rebif. This new option gives you a portable, preassembled, prefilled single-use autoinjector and provides you and your doctor the flexibility of 2 dosing options—44 mcg and 22 mcg.
You still have the option of choosing the prefilled syringe and reusable Rebiject II® autoinjector.
- Rebif is shipped to you in prefilled, preassembled, ready-to-use syringes, so no premixing or assembly is required.
- With Rebiject II and the new Rebif Rebidose, the needle stays covered before and after injection process.
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With Rebif, fewer injections are needed annually compared with Betaseron® (interferon beta-1b) or Extavia® (interferon beta-1b).
Rebif may cause redness, pain, or swelling at the place where an injection was given. Some patients have developed skin infections or areas of severe skin damage (necrosis) requiring treatment by a health care provider. If one of your injection sites becomes swollen and painful or the area looks infected and it doesn't heal within a few days, you should call your health care provider. For more information, please see medication guide.
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3-times-weekly dosing schedule allows for injection-free weekends. Injections should be at least 48 hours apart.
- Rebif has 209 fewer injections per year than Copaxone® (glatiramer acetate injection).†
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Rebif is injected under the skin; Avonex is injected into the muscle.
†No conclusions regarding comparative safety or effectiveness of these products can be drawn from these data.
- If refrigeration is not available, Rebif may be stored at or below room temperature (25°C/77°F) for up to 30 days and away from heat and light.
- If you're just starting on Rebif therapy, the Rebif Titration Pack includes premeasured, prefilled dosing. No mixing or measuring required.
- Rebif is the only relapsing MS treatment with two approved doses—22 mcg and 44 mcg. You and your health care provider can decide which dose is right for you.
Learn more about injection options and support to get you started with Rebif.

