Rebif Rebidose is a preassembled, single-use autoinjector for taking Rebif.
- No assembly required
- Needle stays covered before and after injection process
- Flexible dosing options (44 mcg and 22 mcg)
You should only use Rebif Rebidose after you have received proper training from a medical professional. An MS LifeLines Nurse may be able to provide injection training to you in the comfort of your home.
Speak to your doctor to see if Rebif and Rebif Rebidose are the right options for you.
Meet Rebif Rebidose Watch this video to learn about 1 way to take Rebif.
What people said in a user trial
In a short-term, open-label user trial*:
Do not try to give yourself injections at home until you understand and are comfortable with how to prepare your dose and give the injections.
* In this user trial, Rebif Rebidose was evaluated for 12 weeks by 109 patients with relapsing MS who had previously taken Rebif using the prefilled syringes or the reusable Rebiject II autoinjector.
Rebif Rebidose offers flexible dosing options
At the beginning of Rebif treatment, your healthcare provider may prescribe a titration phase to gradually increase to the intended dosage.
Rebif Rebidose gives you and your doctor the flexibility of 2 dosing options, plus a titration pack:
- 44 mcg autoinjectors have a teal green injector button
- 22 mcg autoinjectors have a yellow injector button
Titration Pack for 44 mcg prescribed dose
Only prefilled syringes can be used to titrate to a 22 mcg prescribed dose.
You should only use Rebif Rebidose after you have received proper training from a medical professional. An MS LifeLines Nurse may be able to provide injection training to you in the comfort of your home. Call 1-877-447-3243 to learn more.
For an injection refresher, watch the Rebif Rebidose injection training video below.
How to use Rebif Rebidose
Remember to always use the injection technique advised by your healthcare provider.
If at any time you have questions or concerns, please contact your healthcare provider or call MS LifeLines® at 1-877-447-3243.
For complete injection instructions, please refer to the Instructions for Use.
Rebif Rebidose injection training Watch MS LifeLines Nurse Shannon demonstrate Rebif Rebidose to Lauren, her patient.
Disposing of after use
Dispose of properly
Put your used Rebif Rebidose autoinjectors in an FDA-cleared sharps disposal container right away after use. Do not throw them away (dispose of) in your household trash.
Use appropriate containers
If you do not have an FDA-cleared sharps disposal container, you may use a properly labeled household container that is made of heavy-duty plastic and can be closed with a tight-fitting, puncture-resistant lid.
Follow community guidelines
When your sharps disposal container is almost full, you will need to follow your community guidelines for the correct way to dispose of it. For more information about safe sharps disposal, go to the FDA's website at: www.fda.gov/safesharpsdisposal.
- Don't dispose of in household trash
Sharps disposal program
Not sure how to dispose of your Rebif Rebidose? EMD Serono, Inc. has partnered with Sharps Compliance. To learn about our disposal program, call MS LifeLines.Call MS LifeLines at 1-877-447-3243.
Storing Rebif Rebidose
- Each Rebif Rebidose autoinjector contains a single dose of Rebif.
- Store Rebif Rebidose in the refrigerator between 36°F and 46°F (2°C to 8°C). Do not freeze. If a refrigerator is not available, it may be stored between 36°F and 77°F (2°C to 25°C) for up to 30 days away from heat and light.
- Do not freeze Rebif or inject Rebif that you suspect has been frozen.
- Keep Rebif Rebidose in its packaging. Open only when needed. Refer to the Rebif drug insert package and Medication Guide for specific storage problems.
Traveling with Rebif Rebidose
- Take 3 Rebif Rebidose autoinjectors with you for each week of your trip. Take some extra in case you are away longer than expected.
- Pack an empty biohazard (sharps) container for proper disposal.
- When traveling by air, always carry Rebif Rebidose autoinjectors in your hand luggage because the aircraft luggage compartment can be cold and Rebif could freeze.
- It is safe to pass Rebif Rebidose autoinjectors through X-ray machines. You may need a note from your healthcare provider to allow you to carry them on an airplane.
- Always check with your airline and your healthcare provider about bringing injectable medication with you.
Rebif Rebidose can go where you go
When you're traveling, you can use your complimentary travel kit that came with your Welcome Kit. If you didn't receive one or would like another, just call MS LifeLines.Call MS LifeLines at 1-877-447-3243.
Important safety precautions
Contact your doctor, nurse, other healthcare professional, or call MS LifeLines, toll-free, at 1-877-447-3243 Monday through Friday, 8 AM to 10 PM ET, and Saturday and Sunday 9 AM to 5 PM ET if:
- You are unsure about how to use the Rebif Rebidose autoinjector
- Rebif Rebidose is not working properly
- You need help with injecting
A live representative answers every call, day or night.
Warnings and safety precautions
- Do not share Rebif Rebidose with anyone. This may result in injury and/or transmission of infectious blood-borne diseases. Adhere to strict safety and antiseptic precautions at all times.
- Always keep Rebif Rebidose and Rebif out of the reach of children.
- Do not point the Rebif Rebidose at yourself or others at any time.
- The device should not be placed in boiling water, a microwave, or an autoclave.
In the unlikely event of failure of your Rebif Rebidose, please contact MS LifeLines at 1-877-447-3243. They will supply a replacement.
For more information about the Rebif Rebidose autoinjector, call MS LifeLines, toll-free, at 1-877-447-3243, Monday through Friday, 8 AM to 10 PM ET, and Saturday and Sunday, 9 AM to 5 PM ET. For complete instructions on the use of the Rebif Rebidose autoinjector, please refer to the Instructions for Use.