Andie P. MS LifeLines Ambassador,
living with relapsing MS

MS LifeLines is a support service designed to help you start and stay on relapsing MS therapy. If you'd like to talk to someone—even before you decide on treatment—MS LifeLines is here for you. Just call 1-877-447-3243 anytime.

You can learn more about MS LifeLines in 1-on-1 Support.

MS LifeLines support staff is here to help

MS-certified nurses

You're not alone. Seven days a week, you can call us for expert MS advice on injecting, managing side effects, and more. We're not just on the phone—we can also come out to your home for injection training.

Patient and care partner ambassadors

We're people living with relapsing MS and the care partners who support them. We know how sometimes it can feel like you're taking on MS alone. That's why you can call and arrange to speak with one of us directly.

Financial Support Specialists

Cost shouldn't be a barrier to finding affordable access to relapsing MS treatment. Whether you have insurance or not, we're here to help you find available financial assistance programs.

Starting off right

As soon as MS LifeLines learns
you have been prescribed Rebif® (interferon beta-1a) by your doctor, with your consent, an MS LifeLines Enrollment Specialist will contact you. He or she will:

  • Schedule a field nurse visit to your home so you can receive personalized 1-on-1 injection training and other therapy support
  • Ship you a Rebif Welcome Kit, which provides information and support to help you start and stay on Rebif as prescribed
  • Connect you to a Financial Support Specialist, who can help you find affordable access to Rebif or navigate your healthcare insurance to help you get the best available coverage for Rebif
  • Answer your questions about living with relapsing MS and taking Rebif therapy

Meet Joanne,
an MS LifeLines Nurse

An MS LifeLines Nurse may be one of the first people you meet when starting Rebif. They're here to help you, from walking you through your first injection to answering any questions you may have while on treatment.

How MS LifeLines Nurses can help

Debbie's story:
Grateful for the help

Debbie’s Story: Grateful for the help

The MS LifeLines Field Nurse came to my house to give me instructions on how to inject. The nurse helped me understand that this injection was going to help me with my MS, and the importance of being on a treatment plan and being able to self-inject. She sat down and really went over everything with me. My family was with me too. Actually, all of us were taught how to inject.

The nurse had such empathy and compassion, and she really worked with me. She made me feel comfortable, and I wasn't afraid to inject while she was there. It just made me feel very relaxed. She wasn't in a hurry. She stayed an hour and forty-five minutes with me!

She kind of made me feel like I had my mom sitting there, and she was telling me everything was going to be okay. I believed her, so it was pretty easy.

The people at MS LifeLines are there for you. You can talk to them about anything. If they can't answer your question, they'll guide you in the right direction. Even if you're a care partner or a friend or a child, you can call MS LifeLines and ask questions about MS.

Debbie B.Race car enthusiast, MS LifeLines Ambassador, living with relapsing MS

This story reflects the personal experience of one person. Results and experiences vary from patient to patient.

Next: $0 co-pay
Important Safety Information and Indication

Important Safety Information


Before beginning treatment, you should discuss the potential benefits and risks associated with Rebif with your healthcare provider.

Rebif can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking Rebif.

  • Behavioral health problems, including depression and suicidal thoughts. You may have mood problems including depression (feeling hopeless or feeling bad about yourself), and thoughts of hurting yourself or suicide
  • Liver problems or worsening of liver problems, including liver failure. Symptoms may include nausea, loss of appetite, tiredness, dark colored urine and pale stools, yellowing of your skin or the white part of your eye, bleeding more easily than normal, confusion, and sleepiness. During your treatment with Rebif you will need to see your healthcare provider regularly and have regular blood tests to check for side effects
  • Serious allergic and skin reactions. Symptoms may include itching, swelling of your face, eyes, lips, tongue or throat, trouble breathing, anxiousness, feeling faint, skin rash, hives, sores in your mouth, or skin blisters and peels
  • Injection site problems. Symptoms at the injection site may include redness, pain, swelling, color changes (blue or black), and drainage of fluid
  • Blood problems. Rebif can affect your bone marrow and cause low red and white blood cell and platelet counts. In some people, these blood cell counts may fall to dangerously low levels. If your blood cell counts become very low, you can get infections and problems with bleeding and bruising. Your healthcare provider may ask you to have regular blood tests to check for blood problems
  • Seizures. Some people have had seizures while taking Rebif

Rebif will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS.

Do not take Rebif if you are allergic to interferon beta, human albumin, or any of the ingredients in Rebif.

Before you take Rebif, tell your healthcare provider if you have or have had any of the following conditions:

  • mental illness, including depression and suicidal behavior
  • liver problems, bleeding problems or blood clots, low blood cell counts, seizures (epilepsy), or thyroid problems
  • you drink alcohol
  • you are pregnant or plan to become pregnant. It is not known if Rebif will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with Rebif
  • you are breastfeeding or plan to breastfeed. It is not known if Rebif passes into your breast milk. You and your healthcare provider should decide if you will use Rebif or breastfeed. You should not do both

Tell your healthcare provider about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effects of Rebif include:

  • flu-like symptoms. You may have flu-like symptoms when you first start taking Rebif. You may be able to manage these flu-like symptoms by taking over-the-counter pain and fever reducers. For many people, these symptoms lessen or go away over time. Symptoms may include muscle aches, fever, tiredness, and chills
  • stomach pain
  • change in liver blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Rebif. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

Refer to the Instructions for Use that comes with Rebif® Rebidose® (interferon beta-1a) autoinjector.


Rebif ® (interferon beta-1a) is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.