Three ways to connect with Rebif
ways to connect

When you start Rebif® (interferon beta-1a), not only will you have the clinical support of a proven treatment for relapsing MS, but also the support of MS LifeLines to help you start and stay on Rebif therapy as prescribed.

MS LifeLines is a community whose mission is to offer connections, understanding, and support to people taking Rebif or considering Rebif, and the family and friends who care for them. The team can answer questions you or your loved ones may have about living with relapsing multiple sclerosis.

From live events to 1-on-1 conversations with other people who have relapsing MS to connecting with an entire community on Facebook, we can help you in a number of ways. If you can’t find what you’re looking for on this site, you can always give us a call at 1-877-447-3243, toll-free, Monday through Friday, 8 AM to 8 PM ET, and Saturday and Sunday from 9 AM to 5 PM ET.

There are over 200 people here for you

Sometimes you need answers. Other times, you need someone to listen. MS LifeLines can offer both. Get in touch with MS LifeLines Nurses, Financial Support Specialists, and real people taking Rebif.

Watch “Why I Chose My Relapsing MS Treatment”

Take part in our Peer Connection Program

When you need to talk, call us and we can match you up with someone who may be going through some of the same issues as you. You can talk to an MS LifeLines Ambassador who is taking Rebif or a care partner who can offer his or her unique perspective. There's no substitute for sharing experiences with people who know what living with MS is all about. Call the Peer Connection Program at 1-866-783-5189.

Peer connection headshots

Join us for 2000+ live events

There are a number of events taking place each year across the US for people living with relapsing MS and their care partners. Led by doctors, nurses, and other multiple sclerosis specialists, they’re a fun way to connect with other people like you while learning more about important topics like understanding treatment goals, the importance of having a plan for your relapsing MS, and more.

Peer connection live event Connect with Rebif peers and care partners

Don't miss our
monthly newsletters

Each month, you can receive a newsletter that will bring you the best of our websites, Facebook page, and YouTube. From information about taking Rebif to more general advice on managing your MS symptoms, our newsletters are one more tool that can help.

Sign up for monthly newsletters

Rebif infographic from our monthly newsletters
Next: Attend a live event
Important Safety Information and Indication

Important Safety Information


Before beginning treatment, you should discuss the potential benefits and risks associated with Rebif with your healthcare provider.

Rebif can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking Rebif.

  • Behavioral health problems, including depression and suicidal thoughts. You may have mood problems including depression (feeling hopeless or feeling bad about yourself), and thoughts of hurting yourself or suicide
  • Liver problems or worsening of liver problems, including liver failure. Symptoms may include nausea, loss of appetite, tiredness, dark colored urine and pale stools, yellowing of your skin or the white part of your eye, bleeding more easily than normal, confusion, and sleepiness. During your treatment with Rebif you will need to see your healthcare provider regularly and have regular blood tests to check for side effects
  • Serious allergic and skin reactions. Symptoms may include itching, swelling of your face, eyes, lips, tongue or throat, trouble breathing, anxiousness, feeling faint, skin rash, hives, sores in your mouth, or skin blisters and peels
  • Injection site problems. Symptoms at the injection site may include redness, pain, swelling, color changes (blue or black), and drainage of fluid
  • Blood problems. Rebif can affect your bone marrow and cause low red and white blood cell and platelet counts. In some people, these blood cell counts may fall to dangerously low levels. If your blood cell counts become very low, you can get infections and problems with bleeding and bruising. Your healthcare provider may ask you to have regular blood tests to check for blood problems
  • Seizures. Some people have had seizures while taking Rebif

Rebif will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS.

Do not take Rebif if you are allergic to interferon beta, human albumin, or any of the ingredients in Rebif.

Before you take Rebif, tell your healthcare provider if you have or have had any of the following conditions:

  • mental illness, including depression and suicidal behavior
  • liver problems, bleeding problems or blood clots, low blood cell counts, seizures (epilepsy), or thyroid problems
  • you drink alcohol
  • you are pregnant or plan to become pregnant. It is not known if Rebif will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with Rebif
  • you are breastfeeding or plan to breastfeed. It is not known if Rebif passes into your breast milk. You and your healthcare provider should decide if you will use Rebif or breastfeed. You should not do both

Tell your healthcare provider about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effects of Rebif include:

  • flu-like symptoms. You may have flu-like symptoms when you first start taking Rebif. You may be able to manage these flu-like symptoms by taking over-the-counter pain and fever reducers. For many people, these symptoms lessen or go away over time. Symptoms may include muscle aches, fever, tiredness, and chills
  • stomach pain
  • change in liver blood tests

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Rebif. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects.

Refer to the Instructions for Use that comes with Rebif® Rebidose® (interferon beta-1a) autoinjector.


Rebif® (interferon beta-1a) is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.